Low FODMAP diets have raised concerns as they can alter the microbiota towards an undesired composition. A typical UK diet contains on average 29.6 g of FODMAPs the single largest component being fructose, either monomeric or as fructans, which averages 16.6 g / day while a typical patient following dietary advice for a low FODMAP diet reduces approximately by half to a total of 17.7 g of FODMAP. These complex carbohydrates have been grouped as fermentable oligo-, di-, mono-saccharides and polyols (FODMAPs) and dietary FODMAP restriction has been shown to relieve IBS symptoms.

However intake of prebiotics may be limited by GI symptoms such as bloating, flatulence and abdominal discomfort. Ingestion of ‘prebiotics’ that preferentially stimulate colonic bacteria, such as oligofructose and inulin, has been shown to reduce markers of metabolic syndrome while increasing the abundance of Bifidobacteria and butyrate producers. Poorly digested, fermentable carbohydrates are believed to contribute to a healthy diet. PRJEB25589).įunding: The authors received no specific funding for this work.Ĭompeting interests: The authors have declared that no competing interests exist. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: The sequencing data are publicly available in the European Nucleotide Archive (ENA,, acc.no. Received: MaAccepted: JPublished: July 26, 2018Ĭopyright: © 2018 Sloan et al. PLoS ONE 13(7):Įditor: John Green, University Hospital Llandough, UNITED KINGDOM (2018) A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects. Citation: Sloan TJ, Jalanka J, Major GAD, Krishnasamy S, Pritchard S, Abdelrazig S, et al.

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